L\u2019autof\u00e0gia \u00e9s un proc\u00e9s cel\u00b7lular molt complex i encara poc conegut, que incorpora la participaci\u00f3 d\u2019un elevat nombre de mol\u00e8cules i org\u00e0nuls diferents. Es fonamenta en la necessitat quotidiana que tenen les c\u00e8l\u00b7lules d\u2019eliminar tot all\u00f2 que no necessiten i que impedeix el seu correcte funcionament, i en el proc\u00e9s que ha de tenir lloc a dins d\u2019aquestes, com a m\u00e8tode per a aconseguir energia en situacions d\u2019estr\u00e8s prolongades.<\/span><\/p>\n Aquest treball es centra en la investigaci\u00f3 de dues prote\u00efnes conegudes (Rab7 i TBC1D15), en la determinaci\u00f3 de la relaci\u00f3 que existeix entre elles en possibles processos autof\u00e0gics i en la recerca sobre la participaci\u00f3 de les macromol\u00e8cules per separat en el proc\u00e9s de degradaci\u00f3. Per aquesta ra\u00f3, l\u2019objectiu de l\u2019experiment realitzat \u00e9s determinar si existeix algun tipus d\u2019interacci\u00f3 entre les prote\u00efnes i en el cas que existeixi, si aquesta pot provocar algun nou canvi o implicaci\u00f3 en el transcurs normal d\u2019un procediment autof\u00e0gic.\u00a0<\/span><\/p>\n Al llarg del treball s\u2019han utilitzat dues t\u00e8cniques diferents (immunofluoresc\u00e8ncia i coimmunoprecipitaci\u00f3) per a intentar demostrar la hip\u00f2tesi que proposa la interacci\u00f3 entre TBC1D15 i Rab7. Per a poder realitzar-ho, s\u2019ha fet \u00fas de tres variables comunes en les dues proves i de tres controls presents nom\u00e9s en la segona. S\u2019han agafat com a base les dues t\u00e8cniques anomenades i s\u2019han explicat tots els procediments necessaris per a la obtenci\u00f3 de resultats.<\/span><\/p>\n \u00a0L\u2019an\u00e0lisi de resultats que t\u00e9 lloc posteriorment, sembla indicar que existeix la interacci\u00f3 entre les prote\u00efnes anomenades i la participaci\u00f3 de TBC1D15 en processos autof\u00e0gics. Tot i aix\u00ed, es determina per certes raons, que els resultats no s\u00f3n prou precisos o significatius. En definitiva, \u00e9s necessari repetir aquests procediments experimentals per a poder constatar la informaci\u00f3 ja publicada en altres textos cient\u00edfics en refer\u00e8ncia a les prote\u00efnes. S\u2019han de seguir investigant tots els detalls que tenen a veure amb l\u2019autof\u00e0gia, doncs \u00e9s un camp molt especialitzat i que de moment, genera m\u00e9s dubtes que respostes.<\/span><\/p>\n L\u2019alumna Laia Parareda de la Osa , de 2n de Batxillerat, ha rebut el Premi BATX2LAB 2021, organitzat pel Parc Cient\u00edfic de la Universitat de Barcelona (UB), pel seu Treball de Recerca \u201c Autof\u00e0gia, el proc\u00e9s desconegut de degradaci\u00f3 cel\u00b7lular “tutoritzat per la professora Marisol Cabral Salvadores. Enhoabona !!! A continuaci\u00f3 podeu llegir l’abstract del […]<\/p>\n","protected":false},"author":26,"featured_media":6944,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1,29,197],"tags":[],"class_list":["post-6942","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general","category-portada","category-premis"],"post_mailing_queue_ids":[],"_links":{"self":[{"href":"https:\/\/agora.xtec.cat\/iesjaumecallis\/wp-json\/wp\/v2\/posts\/6942","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/agora.xtec.cat\/iesjaumecallis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/agora.xtec.cat\/iesjaumecallis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/agora.xtec.cat\/iesjaumecallis\/wp-json\/wp\/v2\/users\/26"}],"replies":[{"embeddable":true,"href":"https:\/\/agora.xtec.cat\/iesjaumecallis\/wp-json\/wp\/v2\/comments?post=6942"}],"version-history":[{"count":3,"href":"https:\/\/agora.xtec.cat\/iesjaumecallis\/wp-json\/wp\/v2\/posts\/6942\/revisions"}],"predecessor-version":[{"id":6956,"href":"https:\/\/agora.xtec.cat\/iesjaumecallis\/wp-json\/wp\/v2\/posts\/6942\/revisions\/6956"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/agora.xtec.cat\/iesjaumecallis\/wp-json\/wp\/v2\/media\/6944"}],"wp:attachment":[{"href":"https:\/\/agora.xtec.cat\/iesjaumecallis\/wp-json\/wp\/v2\/media?parent=6942"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/agora.xtec.cat\/iesjaumecallis\/wp-json\/wp\/v2\/categories?post=6942"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/agora.xtec.cat\/iesjaumecallis\/wp-json\/wp\/v2\/tags?post=6942"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}![\"\"](\"https:\/\/agora.xtec.cat\/iesjaumecallis\/wp-content\/uploads\/usu113\/2021\/03\/P3181964.jpg\")
<\/p>\n","protected":false},"excerpt":{"rendered":"